Most people will experience joint pain at some point, and it has the potential to take over their lives completely. Usually caused by inflammation or cartilage breakdown, it often occurs simply due to old age or the wear and tear your body experiences daily.
However, more severe joint pain is often caused by an autoimmune disease, such as various forms of arthritis. In the early stages, physical medicine can potentially alleviate joint pain, but as it progresses, people will often turn to prescription anti-inflammatory chemicals and other medications to seek relief.
Unfortunately, while these pain relievers can be very effective, they can also often cause side effects. Natural remedies with anti-inflammatory benefits are usually a far better option, as they can reduce joint inflammation and pain like prescription drugs while being much safer.
The only issue is that certain supplements for joint pain are far more effective than others, so it can be hard to know which to pick. That is why we have made the following guide to the ten best joint health supplements on the market in 2024 to help everyone find the perfect one for them.
Let's go to our guide to the ten best supplements for joint pain in 2024. We tested supplements based on vital criteria like their ingredients, the pain-relieving effects they produce, and even their price to compile a list with a perfect option for everyone.
FlexAgain
Joint Buddy
Physio Flex Pro
Nuzena Joint Support +
Relief Factor
Vimerson Health Vegan Glucosamine Chondroitin MSM & Burdock Root
Joint Buddy Omega
Solgar Glucosamine, Hyaluronic Acid, Chondroitin, MSM
Osteo Bi-Flex One Per Day
Animal Flex
FlexAgain is a powerful joint health supplement created using the optimal doses of a wide range of natural ingredients that have been clinically proven to reduce joint pain. It supports the joints from all angles while benefitting the rest of your body in various other ways. It is suitable for almost everyone.
Its potent anti-inflammatory properties neutralize free radicals, prevent oxidative stress and damage, reduce inflammation, combat joint stiffness and swelling, boost connective tissue growth and joint flexibility, function, lubrication, mobility, and repair, and prevent or treat all forms of arthritis.
The ingredients have then been carefully chosen to support each other. For example, turmeric supplements need a bioavailability enhancer like ginger to produce maximum effects. These supplements are made in GMP-certified facilities with a 90-day full money-back guarantee.
Ingredients: glucosamine sulfate, chondroitin sulfate, omega-3 fatty acids, curcumin extract (turmeric), ginger extract, blue galangal extract, bromelain, resveratrol, boswellic acid, MSM (methylsulfonylmethane), vitamin K, and vitamin D
Packed with ingredients proven to provide joint pain relief
The formula is optimized to ensure the ingredients support each other
It is entirely safe for most people and benefits the entire body
All purchases come with a 90-day money-back guarantee
It is pretty pricey and only available directly from the official FlexAgain website.
Not suitable for use by people taking blood thinners
FlexAgain is easily the best option for people looking to take supplements to combat joint pain. Each active compound it uses is natural, optimally dosed, and proven to work, ensuring it can support the joints and relieve pain without causing unpleasant side effects in most people.
Joint Buddy is easily one of the best joint supplements for people on a tighter budget. It provides significant pain relief while being far cheaper than many of the most popular supplements. It does this by mixing some common ingredients with a few less-used ones.
It will boost bone and joint strength; aid bone marrow, connective tissue, and cartilage health, repair, and growth; reduce joint swelling, inflammation, pain, and stiffness; improve flexibility, function, lubrication, mobility, and joint health, and combat all forms of arthritis and the pain and symptoms it causes.
This offers benefits like producing a moderate antidepressant effect and improving blood sugar, cholesterol, energy, hormone levels, and blood cell, DNA, nerve, and brain health. We don't rank it first because it is nowhere near as potent as FlexAgain.
Ingredients: vitamin A, vitamin B1, vitamin B2, vitamin B3, vitamin B6, vitamin B12, vitamin C, vitamin E, selenium, zinc, copper, boron, manganese, chromium, glucosamine sulfate, chondroitin sulfate, green-lipped sea mussel, MSM, l-histidine, alfalfa powder, yuca, devil's claw, and CMO (cetyl myristoleate)
Each natural compound it contains is proven to work and optimally dosed
Offers benefits beyond just supporting the joints
One of the most reasonably priced joint supplements on the market
As quite a new supplement, past customer reviews are rare
Only available directly from the official Joint Buddies website
Joint Buddy is easily the best-value joint supplement on the market in 2024. While it is not as potent as FlexAgain, it is still one of the most effective supplements you will find, while its price tag makes it an option that is suitable for use by people on virtually any budget.
Physio Flex Pro is an excellent option for people dealing with osteoarthritis symptoms, as it directly combats joint pain and contains at least one natural chemical compound that helps the body absorb calcium and every essential nutrient in the product much more effectively.
It can combat all osteoarthritis pain, but it appears to be particularly effective at treating one of the most common types, knee osteoarthritis. It can also improve joint function, flexibility, health, and lubrication, repair cartilage structure, and aid the production of cartilage and synovial cells.
The only problem is that many of its ingredients are present in doses lower than those required to produce optimal effects. This means it may not be helpful for people dealing with joint or knee pain not linked to osteoarthritis, even though it is costly.
Ingredients: Selenium citrate, glucosamine hydrochloride, bromelain (from pineapples), ginger root extract with 5% gingerols, turmeric extract with 95% curcuminoids, chondroitin sulfate, MSM, and black pepper fruit extract
Specifically designed to combat osteoarthritis, especially knee osteoarthritis
It will not cause any side effects
It can reduce joint pain and improve joint health and functions
Very expensive
It will not be of much use for joint pain not caused by osteoarthritis
Physio Flex Pro can be an excellent option for people suffering from osteoarthritis and the severe knee pain it often causes. However, its low dosages and high price tag mean that it is far from the best option for most other people.
Nuzena Joint Support + is a reasonably priced, GMO, sugar, hormone, and gluten-free joint supplement. It is designed to prevent or treat joint pain and improve joint and connective tissue health and repair. Its decent glucosamine content can help the cartilage retain water and lubricate the joints.
Ingredients like quercetin and Boswellia extract, a substance found in Indian frankincense trees, benefit people with rheumatoid arthritis. However, a few issues mean it is not as good for anyone else.
The use of quercetin means it is not suitable for people on blood thinners, and many of its ingredient dosages are far too low to produce excellent results in anyone who does not have rheumatoid arthritis. A turmeric supplement that does not also include a bioavailability enhancer is far from ideal.
Ingredients: MSM, boswellia extract, bromelain, turmeric, chondroitin and glucosamine sulfates, quercetin, and methionine
All ingredients are proven by the Arthritis Foundation to support the joints.
Very reasonably priced and widely available
Very useful for people with rheumatoid arthritis
Besides glucosamine, all its ingredients are present in doses far lower than optimal.
It may not be suitable for use by people taking blood-thinning medications
Nuzena Joint Support + is certainly not the right choice for everyone. However, if you are interested in taking supplements to combat rheumatoid arthritis or deal with joint pain while shopping on a tight budget, it may still be the right choice for you.
Relief Factor is an anti-inflammatory supplement made to relieve joint pain safely. It exclusively uses natural ingredients and targets and fixes the root cause of the issue rather than just masking the pain.
It contains many ingredients supported by the Arthritis Foundation for their ability to reduce joint stiffness, pain, and inflammation and improve joint lubrication and connective tissue repair. There is also evidence that it can actually prevent arthritis from beginning and even benefit overall health.
However, it also contains several ingredients not confirmed to work by any professional bodies regulating supplements, so their use is not guaranteed. A reasonably large serving size and a high price tag could discourage many people from using it.
Ingredients: omega-3 fatty acids, turmeric phospholipid, epimedium aerial, Japanese fleeceflower, cellulose capsule, cellulose powder, stearic acid from a vegetable source, silica, gelatin, glycerine, vitamin E (as natural d-alpha tocopherol) from soy, and an enteric coating
It contains some ingredients that are proven to help combat arthritis
It is one of the only supplements made actually to help prevent arthritis
It has quite a hefty price tag and serving size
Some of the ingredients are not conclusively proven to be of any use
If you are looking to use herbal remedies in supplement form to combat psoriatic arthritis or prevent arthritis in the first place, Relief Factor could be a great choice. However, the product has several issues for everyone else, so it is probably not for you.
Vimerson Health Vegan Glucosamine Chondroitin MSM & Burdock Root is a great vegan product. Glucosamine and chondroitin supplements are known to be great for the joints. Still, they are usually unsuitable for people on a plant-based diet, as their active ingredient traditionally comes from fish oil or shellfish.
Here though, the glucosamine comes from a fungus called Aspergillus niger, while phytodroitin is a type of synthetic chondroitin that is produced in a lab. Burdock root extract is a great vegan alternative to fish oil, as it is rich in omega 3s, while standard MSM is used, as it always comes from plant sources.
Unfortunately, vegan glucosamine and chondroitin have not been studied extensively, so we do not know how they work. Most ingredients are in high doses, which may cause issues, and using artificial ingredients may even put some people off.
Ingredients: vegan glucosamine sulfate sodium, vegan MSM, burdock root 4:1 extract, and phytodroitin
Suitable for vegans and people with fish oil or shellfish allergies
Almost all of its ingredients are proven to support the joints
Very reasonably priced
More research is needed to determine the full effects of phytodroitin
Some of the dosages are so high they may cause side effects
It is not ideal for people who do not like using artificial ingredients
Vimerson Health Vegan Glucosamine Chondroitin MSM & Burdock Root is an excellent alternative to traditional chondroitin and glucosamine supplements for people on a plant-based diet. However, if you do not have any dietary limitations, you are probably better off sticking to the real thing.
Joint Buddy Omega is a new omega-3 supplement made exclusively from a potent dose of fish oil. High in EPA and DHA omega-3s (eicosapentaenoic acid and docosahexaenoic acid), the most beneficial fatty acids, it delivers all of the many benefits that these compounds are proven to offer the human body.
What is truly impressive is that it contains such a large amount of these fatty acids while still boasting a low price tag, which gets even lower if you buy in bulk. This makes it another ideal option for people shopping on a tighter budget.
However, it must be noted that only using a single ingredient means it cannot produce the diverse range of effects that products like FlexAgain can. More information on where the fish oil comes from could also be included.
Ingredients: fish oil
It contains a lot of pure fish oil, which is great for joint lubrication.
Very reasonably priced
Only available directly from the official Joint Buddies website
Its formula is quite limited
Joint Buddy Omega could be a great option if you are looking for supplements packed with fish oil that will lubricate the joints without costing a fortune. Just don't expect it to provide the same diversity of benefits that you would get from a more well-rounded supplement like FlexAgain.
Solgar Glucosamine, Hyaluronic Acid, Chondroitin, and MSM are reasonably priced GMO, shellfish, and gluten-free supplements to improve joint health, mobility, and flexibility. It benefits people with cartilage loss by enhancing cartilage growth and joint cushioning.
Despite its colossal serving size, most of its ingredients are in low dosages. Type II collagen seemingly snuck into the formula is also not ideal, as it comes from animal cartilage, which means that the product is unsuitable for vegans, even though it looks like it is.
Ingredients: shellfish-free glucosamine hydrochloride, chondroitin sulfate, MSM, and BioCell Collagen II (undenatured type II collagen, chondroitin sulfate, and hyaluronic acid)
It only contains high-quality, gluten-, GMO-, and shellfish-free ingredients proven to work.
Very reasonably priced and easy to obtain
Many of the ingredient dosages are too low to produce their full effects
Not suitable for vegans
Solgar Glucosamine, Hyaluronic Acid, Chondroitin, and MSM may be one of the better options on the market for people who are worried about cartilage loss. However, due to several issues with the product, there are probably better options for most people.
Osteo Bi-Flex One Per Day is a gluten-free supplement designed to relieve joint pain in seven days. It is also reasonably priced and requires only one pill daily, so it is suitable for virtually everyone.
It can combat arthritis and joint pain, improve the health and repair of the cartilage, reduce cytokine levels, free radicals, inflammation, oxidative damage and stress, and connective tissue degradation, and even benefit your overall health in various ways.
Unfortunately, its minimal serving size is achieved using low dosages and only a limited range of ingredients, so it will not produce a diverse range of potent effects. The lack of specific bioavailability enhancers also means the glucosamine will be less effective than it usually is.
Ingredients: glucosamine hydrochloride, vitamin D, and Joint Shield 5-LOXIN Advanced boswellia serrata resin extract
It only contains natural ingredients proven to work by the Food And Drug Administration.
It has a very reasonable price tag and serving size
It contains very few ingredients and small dosages
Glucosamine has its efficacy reduced if specific bioavailability enhancers are not present
If you want a budget-friendly joint supplement with a minimal serving size, Osteo Bi-Flex One Per Day can't be beaten. However, if you want more from a product and aren't too worried about the price or serving size, there are far better options.
Animal Flex is a prevalent supplement made by a well-known brand, which makes it ideal for people who prefer products supported by positive word of mouth. It contains proven ingredients that boost the health, lubrication, growth, and repair of the joints and connective tissues.
However, proprietary blends hide most ingredients' exact dosages and effects, making them unsuitable for people taking blood-thinning medications. It is also one of the more expensive joint supplements currently on the market.
Ingredients: MSM, glucosamine and chondroitin sulfates, flax seed oil cetyl myristoleate, ginger root extract, turmeric root extract, Boswellia serrata extract, quercetin, bromelain, vitamins C and E, zinc, selenium, and manganese
Most of its ingredients are proven to improve your joint and overall health.
Made by a prevalent and respected brand
Well reviewed by many past customers
Most of the ingredient dosages and effects are hidden in proprietary blends.
Not all of the ingredients have been conclusively proven to work
Very expensive
Not suitable for vegans, people with soy allergies, or those taking blood thinning medications
Animal Flex is quite a divisive product. It does work to some degree and is a good option for people who like to use the most popular supplements. However, due to the number of issues it faces, if you aren't worried about a supplement's social standing, there are far better options on this list.
Existing research suggests oral supplements ease joint pain and other arthritis symptoms and are an anti-inflammatory drug while being far safer. There are several good dietary supplements of this kind on the market in 2024, but it is our personal opinion that FlexAgain is the best, and in quite a way.
A powerful anti-inflammatory agent, it is packed with proven natural extracts and antioxidant vitamins like vitamin D, which work in unison to repair cartilage damage, reduce inflammation and joint pain, and improve joint health and functions. This ensures that joint issues will never stop you from living your life.
